Studies on chemotherapy of parasitic helminths: efficacy of artemether on Japanese strain of Schistosoma japonicum in mice.
M. Sano, Akyol Cv, Anchalee Tungtrongchitr, Ito M, Akira Ishih
Abstract
M. Sano, Akyol Cv, Anchalee Tungtrongchitr, Ito M, Akira Ishih
Abstract
Effects of artemether were examined on Schistosoma japonicum in mice. When the drug was given at a daily dosage of 200 mg/kg for 4 successive days from 46 days post-infection, a significant reduction in worm recovery was observed. A significant reduction in size of worms from the medicated mice was also seen compared with that from non-medicated controls.
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Effects of artemether were examined on Schistosoma japonicum in mice. When the drug was given at a daily dosage of 200 mg/kg for 4 successive days from 46 days post-infection, a significant reduction in worm recovery was observed. A significant reduction in size of worms from the medicated mice was also seen compared with that from non-medicated controls.
Key concepts: Schistosoma japonicum, Artemether, Anthelmintic, Schistosomiasis, Helminths, Helminthiasis, Praziquantel, Biology