Quantitative Analysis of Serum Level Alanine and Aspartate Aminotransferases, γ-Glutamyl Transferase and Alkaline Phospatase as Predictor of Liver Diseases
Debasish Sahoo, M S Rukmini, Ravitosh Ray
Abstract
Debasish Sahoo, M S Rukmini, Ravitosh Ray
Abstract
The diagnostic evaluation of different enzymes associated to liver such as Alanine Amino Transferase(ALT), Aspartate Amino Transferase(AST) and Gamma Glutamyl Transferase(GGT) can give a easy follow through for detection of liver homeostasis. The hepatic diseases can be better evaluated by analyzing the serum levels of alanine and aspartate amino transferase and Alkaline Phospatase (ALP). The study includes serum level of enzymes of hepatic disorders such as alcoholic liver disease, hepatitis, and liver cirrhosis. The serum level of ALT, AST, GGT and ALP were analysed by their standardized methods . There was a significant relationship between ALT and GGT. Comparative elevation in the above discussed enzyme indicates the nature and degree of the hepatic damage.
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The diagnostic evaluation of different enzymes associated to liver such as Alanine Amino Transferase(ALT), Aspartate Amino Transferase(AST) and Gamma Glutamyl Transferase(GGT) can give a easy follow through for detection of liver homeostasis. The hepatic diseases can be better evaluated by analyzing the serum levels of alanine and aspartate amino transferase and Alkaline Phospatase (ALP). The study includes serum level of enzymes of hepatic disorders such as alcoholic liver disease, hepatitis, and liver cirrhosis. The serum level of ALT, AST, GGT and ALP were analysed by their standardized methods . There was a significant relationship between ALT and GGT. Comparative elevation in the above discussed enzyme indicates the nature and degree of the hepatic damage.
Key concepts: Transferase, Alanine, Internal medicine, Alkaline phosphatase, Enzyme, Cirrhosis, Biochemistry, Aspartate Aminotransferases