Formulation Of Fresh 2% Glutaraldehyde For Pulpotmy In Primary Teeth
Indian Journal, Gaurav Setya, Amit Khatri, Bhojraj Nandlal
Abstract
Indian Journal, Gaurav Setya, Amit Khatri, Bhojraj Nandlal
Abstract
Glutaraldehyde is recommended for pulpotmy in primary teeth but main disadvantage of glutaraldehyde is shelf life , which is less than one year and it has to be freshly prepared before using as pulpotmy agent so in this study formulation of fresh 2% Glutaraldehyde for pulpomy of primary teeth is discussed . limitations which have prevented the widespread use of glutaraldehyde as a pulpotomy agent. The most serious of these limitations is a result of the chemical properties of glutaraldehyde. In aqueous solution, glutaraldehyde is mildly acidic, relatively inert, and very stable. Elevation of the pH of an aqueous glutaraldehyde solution increases the m i c r o b i c i d a l a c t i o n o f t h e glutaraldehyde. Unfortunately, at high pH, glutaraldehyde polymerizes, thereby losing that microbicidal activity. A buffer can be used to maintain the pH of the solution at a mildly alkaline level, i.e., at near physiological pH, and sodium phosphate buffer has been used for that [5] purpose
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Glutaraldehyde is recommended for pulpotmy in primary teeth but main disadvantage of glutaraldehyde is shelf life , which is less than one year and it has to be freshly prepared before using as pulpotmy agent so in this study formulation of fresh 2% Glutaraldehyde for pulpomy of primary teeth is discussed . limitations which have prevented the widespread use of glutaraldehyde as a pulpotomy agent. The most serious of these limitations is a result of the chemical properties of glutaraldehyde. In aqueous solution, glutaraldehyde is mildly acidic, relatively inert, and very stable. Elevation of the pH of an aqueous glutaraldehyde solution increases the m i c r o b i c i d a l a c t i o n o f t h e glutaraldehyde. Unfortunately, at high pH, glutaraldehyde polymerizes, thereby losing that microbicidal activity. A buffer can be used to maintain the pH of the solution at a mildly alkaline level, i.e., at near physiological pH, and sodium phosphate buffer has been used for that [5] purpose
Key concepts: Glutaraldehyde, Aqueous solution, Chemistry, Buffer solution, Nuclear chemistry, Chromatography, Organic chemistry