2013•Unpublished venueRequires access

Formulation Of Fresh 2% Glutaraldehyde For Pulpotmy In Primary Teeth

Indian Journal, Gaurav Setya, Amit Khatri, Bhojraj Nandlal

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Abstract

Glutaraldehyde is recommended for pulpotmy in primary teeth but main disadvantage of glutaraldehyde is shelf life , which is less than one year and it has to be freshly prepared before using as pulpotmy agent so in this study formulation of fresh 2% Glutaraldehyde for pulpomy of primary teeth is discussed . limitations which have prevented the widespread use of glutaraldehyde as a pulpotomy agent. The most serious of these limitations is a result of the chemical properties of glutaraldehyde. In aqueous solution, glutaraldehyde is mildly acidic, relatively inert, and very stable. Elevation of the pH of an aqueous glutaraldehyde solution increases the m i c r o b i c i d a l a c t i o n o f t h e glutaraldehyde. Unfortunately, at high pH, glutaraldehyde polymerizes, thereby losing that microbicidal activity. A buffer can be used to maintain the pH of the solution at a mildly alkaline level, i.e., at near physiological pH, and sodium phosphate buffer has been used for that [5] purpose

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Glutaraldehyde is recommended for pulpotmy in primary teeth but main disadvantage of glutaraldehyde is shelf life , which is less than one year and it has to be freshly prepared before using as pulpotmy agent so in this study formulation of fresh 2% Glutaraldehyde for pulpomy of primary teeth is discussed . limitations which have prevented the widespread use of glutaraldehyde as a pulpotomy agent. The most serious of these limitations is a result of the chemical properties of glutaraldehyde. In aqueous solution, glutaraldehyde is mildly acidic, relatively inert, and very stable. Elevation of the pH of an aqueous glutaraldehyde solution increases the m i c r o b i c i d a l a c t i o n o f t h e glutaraldehyde. Unfortunately, at high pH, glutaraldehyde polymerizes, thereby losing that microbicidal activity. A buffer can be used to maintain the pH of the solution at a mildly alkaline level, i.e., at near physiological pH, and sodium phosphate buffer has been used for that [5] purpose

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Available abstract

Glutaraldehyde is recommended for pulpotmy in primary teeth but main disadvantage of glutaraldehyde is shelf life , which is less than one year and it has to be freshly prepared before using as pulpotmy agent so in this study formulation of fresh 2% Glutaraldehyde for pulpomy of primary teeth is discussed . limitations which have prevented the widespread use of glutaraldehyde as a pulpotomy agent. The most serious of these limitations is a result of the chemical properties of glutaraldehyde. In aqueous solution, glutaraldehyde is mildly acidic, relatively inert, and very stable. Elevation of the pH of an aqueous glutaraldehyde solution increases the m i c r o b i c i d a l a c t i o n o f t h e glutaraldehyde. Unfortunately, at high pH, glutaraldehyde polymerizes, thereby losing that microbicidal activity. A buffer can be used to maintain the pH of the solution at a mildly alkaline level, i.e., at near physiological pH, and sodium phosphate buffer has been used for that [5] purpose

Key concepts: Glutaraldehyde, Aqueous solution, Chemistry, Buffer solution, Nuclear chemistry, Chromatography, Organic chemistry

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