Epidermal Inclusion Cyst of Buccal Mucosa: A Rare Case Report

Epidermal inclusion cysts are the result of implantation of epidermal element which is followed by its cystic trans- formation. The enucleation of cyst is the well established treatment modality. We are presenting a rare case report of epidermal inclusion cyst of buccal mucosa along with relevant literature review. Introduction- Epidermal inclusion cysts are the result of implantation of epi- dermal element which is followed by its cystic transformation. The term epidermoid cyst is used in general context irrespec- tive of the source of epithelium and is more commonly used in place of epidermal inclusion cyst. These cysts should not be called sebaceous cyst as these cysts are not of sebaceous origin. The origin of epidermoid cyst is varied. They developed from the sequestration and implantation of epidermal rest during em- bryonal period, iatrogenic or surgical implantation of epithelium into the oral cavity mesenchymal tissues or due to occlusion of pilosebaceous unit. The lipid pattern analysis demonstrates simi- larity with epidermis and is different from sebaceous cysts. Ad- ditionally, epidermoid cysts express cytokeratin 1 and 10, which is present in the suprabasilar layer of the epidermis. The source of the epithelium is often the infundibulum of the hair follicle. The epidermoid cysts are indolent in growth and slowly progress over a period of months. These cysts are usually asymptomatic unless secondarily infected. Malignant transformation into basal cell carcinoma or squamous cell carcinoma has been reported but is rare. The males are affected twice more commonly than females. These cysts are firm, round, mobile and contain thick cheesy material. Sites commonly involved are face, trunk, neck, extremities and the scalp. Multiple epidermoid cysts is one of the manifestation of the Gardner's syndrome. Surgical removal of the cyst is the mainstay of the treatment and recurrence is