3- Central Giant Cell Granuloma of the Jaw Bones: A Review

Central giant cell granuloma (CGCG) is an uncommon, benign, proliferative, and nonodontogenic lesion whose etiology is not defined. Thought to represent a reparative response to intrabony haemorrhage and inflammation, CGCG was once regarded as a reactive lesion. Central giant cell granuloma usually is an asymptomatic lesion, which may become evident during routine radiographic examination or as a result of painless but visible expansion of the affected jaw. The clinical differential diagnosis for a solitary or multilocular CGCG includes ameloblastoma, odontogenic myxoma, and odontogenic keratocyst. Here, we present a review on the clinical, radiological, histological features of central giant cell granuloma along with discussion on treatment modalities.