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Effect of Garlic Extract on Esterases Activity in Tissue of Male Albino Rats

Sashank Srivastava

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Abstract

The prophylactic efficacy of garlic (Allium sativum Linn.) extract was studied on some biochemical parameters in male albino rats. The garlic extract was tested in three different doses 1, 2 and 4ml/ kg body weight daily for a period of 7, 14, 21 and 28 days. The significant (P<0.01) increase in Acid Phosphatase (AcPase) and Alkaline Phosphatase (AlPase) was observed when rats were fed with low and medium dose whereas significant (P<0.01) decreased was observed in these parameters when rats were fed with 4ml/kg body weight of garlic extract. The above study clearly indicated that phosphomonoesterases substantially affected by garlic extract and may be used as convenient markers in teratological studies.

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What this paper is about

The prophylactic efficacy of garlic (Allium sativum Linn.) extract was studied on some biochemical parameters in male albino rats. The garlic extract was tested in three different doses 1, 2 and 4ml/ kg body weight daily for a period of 7, 14, 21 and 28 days. The significant (P<0.01) increase in Acid Phosphatase (AcPase) and Alkaline Phosphatase (AlPase) was observed when rats were fed with low and medium dose whereas significant (P<0.01) decreased was observed in these parameters when rats were fed with 4ml/kg body weight of garlic extract. The above study clearly indicated that phosphomonoesterases substantially affected by garlic extract and may be used as convenient markers in teratological studies.

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Available abstract

The prophylactic efficacy of garlic (Allium sativum Linn.) extract was studied on some biochemical parameters in male albino rats. The garlic extract was tested in three different doses 1, 2 and 4ml/ kg body weight daily for a period of 7, 14, 21 and 28 days. The significant (P<0.01) increase in Acid Phosphatase (AcPase) and Alkaline Phosphatase (AlPase) was observed when rats were fed with low and medium dose whereas significant (P<0.01) decreased was observed in these parameters when rats were fed with 4ml/kg body weight of garlic extract. The above study clearly indicated that phosphomonoesterases substantially affected by garlic extract and may be used as convenient markers in teratological studies.

Key concepts: Allium sativum, Alkaline phosphatase, Acid phosphatase, Body weight, Chemistry, Biology, Traditional medicine, Food science

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Effect of Garlic Extract on Esterases Activity in Tissue of Male Albino Rats — Research Paper | ScholarLens