2015•Unpublished venueRequires access
Inhibition of Human Immunodeficiency Virus (HIV- 1) by Hedera helix L. Extracts and Phytoconstituents
Khaled Rashed, Mengting Luo, Lintao Zhang, Yong‐Tang Zheng, Khaled Nabih, Zaki Rashed
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Abstract
This study deals with the evaluation of anti-HIV-1 effect of Hedera helix L. extracts and also the investigation of the phytoconstituents from the extracts of the plant. Chloroform, ethyl acetate and methanol 80% extracts of Hedera helix aerial parts were tested for their anti-HIV-1 activity using the syncytia formation assay. Methanol 80% Hedera helix aerial parts has shown antiHIV-1activity and the other extracts were less active. Phytochemical profile of the plant extracts proves the presence of triterpenes, saponins, flavonoids, tannins and carbohydrates. The results have shown that Hedera helix methanol 80% extract has drug ability as anti- HIV-1 agent.