ScholarLens Back to search
2013•Unpublished venueRequires access

HISTOLOGY AND CYTOGENETIC STUDY OF CHORIONIC VILLUS TISSUE IN FIRST TRIMESTER ABORTION

Shahin Kazi, Sonali Vidhale, S. V. Kotwaliwale

Open publisher page 1 citations

Abstract

Pregnancy loss is a very common entity observed in obstetric practice.Most commonly it occurs in first trimester abortions. In this study we are doing histological and cytogenetic analysis of chorion villus tissue in first trimester abortion. This will help us to know whether the pregnancy loss was due to chromosomal abnormality. All the selected cases were in the age group 19-40 years. Abnormal karyotype was found in 38 % of the cases. Trisomy was predominated followed by polyploidy, monosomyX, structural anomalies and other abnormality. Regarding histology, the highest precision in categorizing abnormal abortion reached with trisomy and triploidy. It was seen that placental microscopic study alone was not enough to give a proper aeitological diagnosis in case of spontaneous abortion. In conclusion cytogenetic analysis is necessary for differentiating between choromosomally normal and abnormal abortion for further management of the patient.

About this research paper

What this paper is about

Pregnancy loss is a very common entity observed in obstetric practice.Most commonly it occurs in first trimester abortions. In this study we are doing histological and cytogenetic analysis of chorion villus tissue in first trimester abortion. This will help us to know whether the pregnancy loss was due to chromosomal abnormality. All the selected cases were in the age group 19-40 years. Abnormal karyotype was found in 38 % of the cases. Trisomy was predominated followed by polyploidy, monosomyX, structural anomalies and other abnormality. Regarding histology, the highest precision in categorizing abnormal abortion reached with trisomy and triploidy. It was seen that placental microscopic study alone was not enough to give a proper aeitological diagnosis in case of spontaneous abortion. In conclusion cytogenetic analysis is necessary for differentiating between choromosomally normal and abnormal abortion for further management of the patient.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Pregnancy loss is a very common entity observed in obstetric practice.Most commonly it occurs in first trimester abortions. In this study we are doing histological and cytogenetic analysis of chorion villus tissue in first trimester abortion. This will help us to know whether the pregnancy loss was due to chromosomal abnormality. All the selected cases were in the age group 19-40 years. Abnormal karyotype was found in 38 % of the cases. Trisomy was predominated followed by polyploidy, monosomyX, structural anomalies and other abnormality. Regarding histology, the highest precision in categorizing abnormal abortion reached with trisomy and triploidy. It was seen that placental microscopic study alone was not enough to give a proper aeitological diagnosis in case of spontaneous abortion. In conclusion cytogenetic analysis is necessary for differentiating between choromosomally normal and abnormal abortion for further management of the patient.

Key concepts: Abortion, Products of conception, Chorionic villi, Obstetrics, Abnormality, Chromosomal Abnormality, Trisomy, Pregnancy

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
HISTOLOGY AND CYTOGENETIC STUDY OF CHORIONIC VILLUS TISSUE IN FIRST TRIMESTER ABORTION — Research Paper | ScholarLens