2010•Unpublished venueRequires access

Case Report Proarrhythmia Induced by Propafenone: What is the Mechanism?

Francisco Femenía, Jorge Palazzolo, Mauricio Arce, Martin Tc

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Abstract

Propafenone, a Class IC antiarrhythmic drug, is an orally active sodium channel-blocking agent. It is effective in supraventricular tachyarrhythmias and is particularly useful in converting atrial fibrillation to sinus rhythm. In therapeutic doses, it may cause non-cardiac and cardiac toxicity, including proarrhythmia.

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What this paper is about

Propafenone, a Class IC antiarrhythmic drug, is an orally active sodium channel-blocking agent. It is effective in supraventricular tachyarrhythmias and is particularly useful in converting atrial fibrillation to sinus rhythm. In therapeutic doses, it may cause non-cardiac and cardiac toxicity, including proarrhythmia.

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Available abstract

Propafenone, a Class IC antiarrhythmic drug, is an orally active sodium channel-blocking agent. It is effective in supraventricular tachyarrhythmias and is particularly useful in converting atrial fibrillation to sinus rhythm. In therapeutic doses, it may cause non-cardiac and cardiac toxicity, including proarrhythmia.

Key concepts: Proarrhythmia, Propafenone, Supraventricular arrhythmia, Medicine, Sinus rhythm, Antiarrhythmic agent, Drug, Anti-Arrhythmia Agents

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