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Effects of Calcium Channel Blocker, Nicardipine, On Intracranial and Cerebral Perfusion Pressure in Experimental Intracerebral Haemorrhage

Recai Tuncer, Saim Kazan, Cem Açikbas, Mete Sa Veren

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Abstract

Caldum channel blockers have an important role in the therapy of arterial hypertension and eerebral vasospasm, two phenomena which can be assodated with intraeerebral haematoma and inaeased intraaanial pressure, The purpose of this study was to investigate the effects of Nicardipine on intraaanial and eerebral perfusion pressme in animals with experimental intraeranial haematoma formation. Cerebral perfusion pressure (CPP) was 75.12 5.11 mm Hg in the control group. Intraaanial pressure(ICP) showed a signifieant in­ aease with haematoma formation. but no signifieant differenee

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What this paper is about

Caldum channel blockers have an important role in the therapy of arterial hypertension and eerebral vasospasm, two phenomena which can be assodated with intraeerebral haematoma and inaeased intraaanial pressure, The purpose of this study was to investigate the effects of Nicardipine on intraaanial and eerebral perfusion pressme in animals with experimental intraeranial haematoma formation. Cerebral perfusion pressure (CPP) was 75.12 5.11 mm Hg in the control group. Intraaanial pressure(ICP) showed a signifieant in­ aease with haematoma formation. but no signifieant differenee

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Available abstract

Caldum channel blockers have an important role in the therapy of arterial hypertension and eerebral vasospasm, two phenomena which can be assodated with intraeerebral haematoma and inaeased intraaanial pressure, The purpose of this study was to investigate the effects of Nicardipine on intraaanial and eerebral perfusion pressme in animals with experimental intraeranial haematoma formation. Cerebral perfusion pressure (CPP) was 75.12 5.11 mm Hg in the control group. Intraaanial pressure(ICP) showed a signifieant in­ aease with haematoma formation. but no signifieant differenee

Key concepts: Nicardipine, Calcium channel blocker, Cerebral perfusion pressure, Perfusion, Medicine, Vasospasm, Anesthesia, Cerebral vasospasm

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Effects of Calcium Channel Blocker, Nicardipine, On Intracranial and Cerebral Perfusion Pressure in Experimental Intracerebral Haemorrhage — Research Paper | ScholarLens