Effects of Calcium Channel Blocker, Nicardipine, On Intracranial and Cerebral Perfusion Pressure in Experimental Intracerebral Haemorrhage
Recai Tuncer, Saim Kazan, Cem Açikbas, Mete Sa Veren
Abstract
Recai Tuncer, Saim Kazan, Cem Açikbas, Mete Sa Veren
Abstract
Caldum channel blockers have an important role in the therapy of arterial hypertension and eerebral vasospasm, two phenomena which can be assodated with intraeerebral haematoma and inaeased intraaanial pressure, The purpose of this study was to investigate the effects of Nicardipine on intraaanial and eerebral perfusion pressme in animals with experimental intraeranial haematoma formation. Cerebral perfusion pressure (CPP) was 75.12 5.11 mm Hg in the control group. Intraaanial pressure(ICP) showed a signifieant in aease with haematoma formation. but no signifieant differenee
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Caldum channel blockers have an important role in the therapy of arterial hypertension and eerebral vasospasm, two phenomena which can be assodated with intraeerebral haematoma and inaeased intraaanial pressure, The purpose of this study was to investigate the effects of Nicardipine on intraaanial and eerebral perfusion pressme in animals with experimental intraeranial haematoma formation. Cerebral perfusion pressure (CPP) was 75.12 5.11 mm Hg in the control group. Intraaanial pressure(ICP) showed a signifieant in aease with haematoma formation. but no signifieant differenee
Key concepts: Nicardipine, Calcium channel blocker, Cerebral perfusion pressure, Perfusion, Medicine, Vasospasm, Anesthesia, Cerebral vasospasm