The Design of Scaffolds for Use in Tissue Engineering
Tabatabaei Qomi, Naser Kalhor, Hoda Fazaeli
Abstract
Tabatabaei Qomi, Naser Kalhor, Hoda Fazaeli
Abstract
Problems: Tissue engineering (TE) is one of the modern strategies to provide a functional biological tissue equivalent to restore or improve the function of human tissues that lost by disease, traumatic events, or congenital abnormalities. Some essential factors in TE are tissue type and appropriate scaffold. suitable influence on cell viability and proliferation is One of the most important characteristics of a appropriate scaffold for tissue engineering. The purpose of this research was to comparative evaluation of adipose derived stem cells (ADSCs) proliferation rate and their viability on the five different scaffolds. Experimental approach: six different scaffolds were prepared including Alginate, Poly Lactic Glycolic Acid (PLGA), Fibrin glue (FG), Inactive Platelet- Rich Plasma (IPRP), Active Platelet- Rich Plasma (APRP) and Hydroxyapatite/ β
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Problems: Tissue engineering (TE) is one of the modern strategies to provide a functional biological tissue equivalent to restore or improve the function of human tissues that lost by disease, traumatic events, or congenital abnormalities. Some essential factors in TE are tissue type and appropriate scaffold. suitable influence on cell viability and proliferation is One of the most important characteristics of a appropriate scaffold for tissue engineering. The purpose of this research was to comparative evaluation of adipose derived stem cells (ADSCs) proliferation rate and their viability on the five different scaffolds. Experimental approach: six different scaffolds were prepared including Alginate, Poly Lactic Glycolic Acid (PLGA), Fibrin glue (FG), Inactive Platelet- Rich Plasma (IPRP), Active Platelet- Rich Plasma (APRP) and Hydroxyapatite/ β
Key concepts: Tissue engineering, Scaffold, Biomedical engineering, PLGA, Adipose tissue, Fibrin glue, Stem cell, Fibrin