2002•Unpublished venueRequires access

bZIP transcription factors in Arabidopsis The bZIP Research Group (Marc Jakoby et al.)

Marc Jakoby, Bernd Weißhaar, Wolfgang Dröge‐Laser, Jesús Vicente‐Carbajosa, Jens Tiedemann, Thomas Kroj, François Parcy

Abstract

Transcription factors (TFs) play crucial roles inalmost all biological processes. Structurally, TFs areusually classified by their DNA-binding domains:basic region/leucine zipper (bZIP) TFs have a basicregion that binds DNAand a leucine zipperdimerization motif (Box 1). Proteins with bZIPdomains are present in all eukaryotes analysed todate. Some, such as Jun/Fos or CREB, have beenstudied extensively in animals and serve as modelsfor understanding TF–DNAinteractions, ternarycomplex formation and TF post-translationalmodifications (Box 1).

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Key concepts: bZIP domain, Leucine zipper, Basic helix-loop-helix leucine zipper transcription factors, Transcription factor, Activating transcription factor, Genetics, Transcription (linguistics), Biology