ScholarLens Back to search
2014•Unpublished venueRequires access

EVALUATION OF ALBENDAZOLE AGAINST SHEEP STRONGYLES IN FARMS OF KARNATAKA STATE BY DIFFERENT IN VITRO TESTS

Sahil Kumar, C. Renukaprasad, Placid E. D’Souza, B.S. Pradeep

Open publisher page 1 citations

Abstract

Faecal samples of 264 sheep from 4 different sheep farms belonging to three different districts of Karnataka were screened to note the incidence of gastrointestinal nematodes. It was found that 93% of the sheep harboured strongyle infection. The faecal egg counts were found to be light to moderate. The in vitro egg hatch assay was employed to assess the resistance of strongyles in 4 sheep farms. The ED50 value for albendazole ranged between 2.5µg/ml to 6.9 µg/ ml which indicated the resistance of the gastrointestinal nematodes. All the samples were also subjected to another in vitr o test,viz., larval development assay. The values ranged between 3-2µg to 4.2µg / ml which also indicated the development of resistance to albendazole. Larval paralysis assay confirmed the development of resistance to albendazole.

About this research paper

What this paper is about

Faecal samples of 264 sheep from 4 different sheep farms belonging to three different districts of Karnataka were screened to note the incidence of gastrointestinal nematodes. It was found that 93% of the sheep harboured strongyle infection. The faecal egg counts were found to be light to moderate. The in vitro egg hatch assay was employed to assess the resistance of strongyles in 4 sheep farms. The ED50 value for albendazole ranged between 2.5µg/ml to 6.9 µg/ ml which indicated the resistance of the gastrointestinal nematodes. All the samples were also subjected to another in vitr o test,viz., larval development assay. The values ranged between 3-2µg to 4.2µg / ml which also indicated the development of resistance to albendazole. Larval paralysis assay confirmed the development of resistance to albendazole.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Faecal samples of 264 sheep from 4 different sheep farms belonging to three different districts of Karnataka were screened to note the incidence of gastrointestinal nematodes. It was found that 93% of the sheep harboured strongyle infection. The faecal egg counts were found to be light to moderate. The in vitro egg hatch assay was employed to assess the resistance of strongyles in 4 sheep farms. The ED50 value for albendazole ranged between 2.5µg/ml to 6.9 µg/ ml which indicated the resistance of the gastrointestinal nematodes. All the samples were also subjected to another in vitr o test,viz., larval development assay. The values ranged between 3-2µg to 4.2µg / ml which also indicated the development of resistance to albendazole. Larval paralysis assay confirmed the development of resistance to albendazole.

Key concepts: Albendazole, Veterinary medicine, Biology, Larva, Helminths, Botany, Medicine, Ecology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
EVALUATION OF ALBENDAZOLE AGAINST SHEEP STRONGYLES IN FARMS OF KARNATAKA STATE BY DIFFERENT IN VITRO TESTS — Research Paper | ScholarLens