2013•Unpublished venueRequires access

Protein Tertiary Structure Prediction using Data mining Techniques

Chandrayani Rokde, Shital Satyen Telrandhe, Manali M. Kshisagar

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Abstract

Proteins are essential part of our life and participate in virtually every process within a cell. The understanding of protein structures is vital to determine the function of a protein. Protein structure prediction (PSP) from amino acid sequence is one of the high focus problems in bioinformatics today. This is due to the fact that the biological function of the protein is determined by its three dimensional structure. Thus, protein structure prediction is a fundamental area of computational biology. Its importance is intensed by large amounts of sequence data coming from PDB (Protein Data Bank) and the fact that experimentally methods such as X-ray crystallography or Nuclear Magnetic Resonance (NMR)which are used to determining protein structures remains very expensive and time consuming. In this paper computational methods for PSP is discussed and results are taken along with the help of parallel processing server.

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What this paper is about

Proteins are essential part of our life and participate in virtually every process within a cell. The understanding of protein structures is vital to determine the function of a protein. Protein structure prediction (PSP) from amino acid sequence is one of the high focus problems in bioinformatics today. This is due to the fact that the biological function of the protein is determined by its three dimensional structure. Thus, protein structure prediction is a fundamental area of computational biology. Its importance is intensed by large amounts of sequence data coming from PDB (Protein Data Bank) and the fact that experimentally methods such as X-ray crystallography or Nuclear Magnetic Resonance (NMR)which are used to determining protein structures remains very expensive and time consuming. In this paper computational methods for PSP is discussed and results are taken along with the help of parallel processing server.

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Available abstract

Proteins are essential part of our life and participate in virtually every process within a cell. The understanding of protein structures is vital to determine the function of a protein. Protein structure prediction (PSP) from amino acid sequence is one of the high focus problems in bioinformatics today. This is due to the fact that the biological function of the protein is determined by its three dimensional structure. Thus, protein structure prediction is a fundamental area of computational biology. Its importance is intensed by large amounts of sequence data coming from PDB (Protein Data Bank) and the fact that experimentally methods such as X-ray crystallography or Nuclear Magnetic Resonance (NMR)which are used to determining protein structures remains very expensive and time consuming. In this paper computational methods for PSP is discussed and results are taken along with the help of parallel processing server.

Key concepts: Protein structure prediction, Protein structure database, Protein Data Bank, Protein structure, Protein Data Bank (RCSB PDB), Computer science, Protein function prediction, Structural genomics

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