In vitro Anthelmintic Activity of Mentha longifolia (L.) Leaves Against Ascaridia galli
Javid Ahmad, Syed Tanveer, Bilal A. Zargar
Abstract
Javid Ahmad, Syed Tanveer, Bilal A. Zargar
Abstract
2 Abstract: The in vitro anthelmintic activity of the aqueous and hydroalcoholic extracts of Mentha longifolia against Ascardia galli was evaluated in comparison to Fenbendazole. In folklore medicine, M. longifolia (Lamiaceae) is used in the treatment of various gastrointestinal ailments and other conditions. Worm Motility Inhibition (WMI) assay was used for in vitro assessment that revealed anthelmintic effects of crude hydroalcoholic extract (CHE) and crude aqueous extract (CAE) of M. longifolia on live Ascardia galli worms as evident from their paralysis and/or death at 6 h after exposure. Different concentrations (25 mg ml and 1 50 mg ml ) of aqueous and hydroalcoholic extracts were used against A. galli which exhibited concentration 1 and time dependent anthelmintic effects on A. galli. It is concluded that the leaves of M. longifolia possesses significant anthelmintic activity and could be a potential alternative for treating cases of A. galli infections in chickens.
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2 Abstract: The in vitro anthelmintic activity of the aqueous and hydroalcoholic extracts of Mentha longifolia against Ascardia galli was evaluated in comparison to Fenbendazole. In folklore medicine, M. longifolia (Lamiaceae) is used in the treatment of various gastrointestinal ailments and other conditions. Worm Motility Inhibition (WMI) assay was used for in vitro assessment that revealed anthelmintic effects of crude hydroalcoholic extract (CHE) and crude aqueous extract (CAE) of M. longifolia on live Ascardia galli worms as evident from their paralysis and/or death at 6 h after exposure. Different concentrations (25 mg ml and 1 50 mg ml ) of aqueous and hydroalcoholic extracts were used against A. galli which exhibited concentration 1 and time dependent anthelmintic effects on A. galli. It is concluded that the leaves of M. longifolia possesses significant anthelmintic activity and could be a potential alternative for treating cases of A. galli infections in chickens.
Key concepts: Anthelmintic, Ascaridia galli, Fenbendazole, Traditional medicine, Haemonchus contortus, In vitro, Biology, Aqueous extract