2003Bioorganic & Medicinal Chemistry LettersOpen access

Design and synthesis of factor Xa inhibitors and their prodrugs

Yonghong Song, Lane A. Clizbe, C. BHAKTA, Willy Teng, Paul Wong, Brian Huang, Katherine Tran, Uma Sinha, Gary Park, Andrea Reed, Robert M. Scarborough, Bing Zhu

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Key concepts: Prodrug, Amidine, Chemistry, Bioavailability, Pharmacology, Chemical synthesis, Oral administration, Drug

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