2000•PubMedRequires access

[Comparison of circulating antigen detection in schistosomiasis japonica patients using two methods of ELISA].

Qiu Lz, Zhang Yh, Huijun Li, Xue Hc

Abstract

OBJECTIVE: To compare 2 kinds of ELISA methods for detecting circulating antigen in schistosomiasis patients. METHODS: Monoclonal antibody-based dot-ELISA and sandwich ELISA. RESULTS AND CONCLUSION: The positive rates of dot-ELISA were higher than or similar to those of sandwich ELISA, the former being 48.0%-98.8% and the latter being 12.0%-93.8%. The specificities were 95.4%-100% and 90.0%, respectively.

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Key concepts: SCHISTOSOMIASIS JAPONICA, Schistosomiasis, Antigen, Monoclonal antibody, Schistosoma japonicum, Antibody, Virology, Immunology