ScholarLens Back to search
2008•Contemporary EndocrinologyRequires access

Recommended Treatment Modalities for Hyperandrogenism

Michel Pugeat, Nisrin Kaddar, Véronique Raverot

Open publisher page 0 citations

Abstract

SummaryImprovement in androgenic symptoms generally requires ovarian androgen suppression. Insulin sensitizers may also be effective. Androgen suppression (e.g., oral contraceptives or metformin) alone produces modest decreases in the degree of hirsutism; concomitant antiandrogen therapy improves effectiveness considerably. The use of androgen receptor (AR) competitive inhibitors such as spironolactone, flutamide, or cyproterone acetate is recommended for the treatment of dermatologic hyperandrogenic symptoms, principally hirsutism.

About this research paper

What this paper is about

SummaryImprovement in androgenic symptoms generally requires ovarian androgen suppression. Insulin sensitizers may also be effective. Androgen suppression (e.g., oral contraceptives or metformin) alone produces modest decreases in the degree of hirsutism; concomitant antiandrogen therapy improves effectiveness considerably. The use of androgen receptor (AR) competitive inhibitors such as spironolactone, flutamide, or cyproterone acetate is recommended for the treatment of dermatologic hyperandrogenic symptoms, principally hirsutism.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

SummaryImprovement in androgenic symptoms generally requires ovarian androgen suppression. Insulin sensitizers may also be effective. Androgen suppression (e.g., oral contraceptives or metformin) alone produces modest decreases in the degree of hirsutism; concomitant antiandrogen therapy improves effectiveness considerably. The use of androgen receptor (AR) competitive inhibitors such as spironolactone, flutamide, or cyproterone acetate is recommended for the treatment of dermatologic hyperandrogenic symptoms, principally hirsutism.

Key concepts: Cyproterone acetate, Flutamide, hirsutism, Hyperandrogenism, Antiandrogen, Medicine, Spironolactone, Cyproterone

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Recommended Treatment Modalities for Hyperandrogenism — Research Paper | ScholarLens