2006•Journal of Heterocyclic ChemistryRequires access

Chemistry of quinuclidines as nitrogen bicyclic bridged‐ring structures

Wafaa S. Hamama, Osama M. Abd El‐Magid, Hanafi H. Zoorob

Abstract

Abstract This review summarises the structure, basicity, asymmetric organocatalysis, synthesis and reactions of quinuclidines. Quinuclidines are bicyclic saturated pyridin‐containing compounds with rigid structures and a ring‐juncture nitrogen atom. This review covers the period from 1984–2005.

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Key concepts: Chemistry, Bicyclic molecule, Nitrogen atom, Ring (chemistry), Nitrogen, Organocatalysis, Stereochemistry, Medicinal chemistry