2009•Cell Motility and the CytoskeletonOpen access
Structures of kinesin motor proteins
Alexander Marx, Andreas Hoenger, Eckhard Mandelkow�
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Abstract
Almost 25 years of kinesin research have led to the accumulation of a large body of knowledge about this widespread superfamily of motor and nonmotor proteins present in all eukaryotic cells. This review covers developments in kinesin research with an emphasis on structural aspects obtained by X-ray crystallography and cryoelectron microscopy 3-D analysis on kinesin motor domains complexed to microtubules.
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