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2002•Journal of BacteriologyOpen access

The Gene yjfQ Encodes the Repressor of the yjfR-X Regulon ( ula ), Which Is Involved in l -Ascorbate Metabolism in Escherichia coli

Evangelina Campos, Juan Aguilar, Laura Baldomà, Josefa Badı́a

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Abstract

Mutations in yjfQ allowed us to identify this gene as the regulator of the operon yjfS-X (ula operon), reported to be involved in L-ascorbate metabolism. Inactivation of this gene renders constitutive the expression of the ula operon, indicating that YjfQ acts as a repressor. We also demonstrate that this repressor regulates the nearby yjfR gene, which in this way constitutes a regulon with the ula operon.

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Mutations in yjfQ allowed us to identify this gene as the regulator of the operon yjfS-X (ula operon), reported to be involved in L-ascorbate metabolism. Inactivation of this gene renders constitutive the expression of the ula operon, indicating that YjfQ acts as a repressor. We also demonstrate that this repressor regulates the nearby yjfR gene, which in this way constitutes a regulon with the ula operon.

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Available abstract

Mutations in yjfQ allowed us to identify this gene as the regulator of the operon yjfS-X (ula operon), reported to be involved in L-ascorbate metabolism. Inactivation of this gene renders constitutive the expression of the ula operon, indicating that YjfQ acts as a repressor. We also demonstrate that this repressor regulates the nearby yjfR gene, which in this way constitutes a regulon with the ula operon.

Key concepts: Regulon, Operon, Repressor, Biology, Gene, Escherichia coli, Genetics, L-arabinose operon

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The Gene yjfQ Encodes the Repressor of the yjfR-X Regulon ( ula ), Which Is Involved in l -Ascorbate Metabolism in Escherichia coli — Research Paper | ScholarLens