2005Unpublished venueRequires access

Medical Case Study NEW CASES OF LEISHMANIASIS VISCERALIS IN SOUTHEAST BULGARIA

B. Chakarova, V. Filipova, B. Stephanova, K. Karastojanova

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Abstract

Visceral leishmaniasis (VL) is a vector-borne protozoan infection transmitted by Phlebotomine sandflies, the primary hosts of the infective Leishmania donovani In the Mediterranean region VL is caused by Leishmania infantum. We studied two VL-infected men (50- and 67-years old) from Stara Zagora region of Bulgaria. Clinical diagnosis was based on the clinical signs of visceral leishmaniasis such as splenomegaly, hepatomegaly, and high undulating fever. Leishmanial parasites were assayed by light microscopy of bone marrow and anti-Leishmania infantum antibodies were looked for via indirect immunofluorescence. Was used Glucantime (N-methyl glucamine antimoniate) 20 mg/ for antileishmanial therapy. LV in the older man was complicated and had finished by exitus letalis.

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What this paper is about

Visceral leishmaniasis (VL) is a vector-borne protozoan infection transmitted by Phlebotomine sandflies, the primary hosts of the infective Leishmania donovani In the Mediterranean region VL is caused by Leishmania infantum. We studied two VL-infected men (50- and 67-years old) from Stara Zagora region of Bulgaria. Clinical diagnosis was based on the clinical signs of visceral leishmaniasis such as splenomegaly, hepatomegaly, and high undulating fever. Leishmanial parasites were assayed by light microscopy of bone marrow and anti-Leishmania infantum antibodies were looked for via indirect immunofluorescence. Was used Glucantime (N-methyl glucamine antimoniate) 20 mg/ for antileishmanial therapy. LV in the older man was complicated and had finished by exitus letalis.

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Available abstract

Visceral leishmaniasis (VL) is a vector-borne protozoan infection transmitted by Phlebotomine sandflies, the primary hosts of the infective Leishmania donovani In the Mediterranean region VL is caused by Leishmania infantum. We studied two VL-infected men (50- and 67-years old) from Stara Zagora region of Bulgaria. Clinical diagnosis was based on the clinical signs of visceral leishmaniasis such as splenomegaly, hepatomegaly, and high undulating fever. Leishmanial parasites were assayed by light microscopy of bone marrow and anti-Leishmania infantum antibodies were looked for via indirect immunofluorescence. Was used Glucantime (N-methyl glucamine antimoniate) 20 mg/ for antileishmanial therapy. LV in the older man was complicated and had finished by exitus letalis.

Key concepts: Visceral leishmaniasis, Leishmania infantum, Meglumine antimoniate, Leishmaniasis, Leishmania, Leishmania donovani, Medicine, Virology

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