A Facile Synthesis of α,α′-bis(Substituted Benzylidene) Cycloalkanones Catalyzed by KF/Al2O3 Under Ultrasound Irradiation
Ji‐Tai Li, Wenzhi Yang, Guofeng Chen, Tong‐Shuang Li
Abstract
Ji‐Tai Li, Wenzhi Yang, Guofeng Chen, Tong‐Shuang Li
Abstract
The condensation of the cyclopentanone or cyclohexanone with aromatic aldehydes catalyzed by KF/Al2O3 in MeOH under ultrasound irradiation, result the corresponding 2,5-bis(substituted benzylidene) cyclopentanones or 2,6-bis(substituted benzylidene) cyclohexanones in good yields.
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The condensation of the cyclopentanone or cyclohexanone with aromatic aldehydes catalyzed by KF/Al2O3 in MeOH under ultrasound irradiation, result the corresponding 2,5-bis(substituted benzylidene) cyclopentanones or 2,6-bis(substituted benzylidene) cyclohexanones in good yields.
Key concepts: Chemistry, Cyclopentanone, Cyclohexanone, Catalysis, Condensation, Medicinal chemistry, Yield (engineering), Irradiation