Fatal Case of Toxic Shock-Like Syndrome Due to Group C Streptococcus Associated with Superantigen Exotoxin
Tony M. Korman, Anthony Boers, Travis M. Gooding, Nigel Curtis, Kumar Visvanathan
Abstract
Tony M. Korman, Anthony Boers, Travis M. Gooding, Nigel Curtis, Kumar Visvanathan
Abstract
Group C streptococci have been reported to cause invasive disease similar to that classically associated with group A streptococcus (GAS). We describe a fatal case of toxic shock-like syndrome due to Streptococcus equi subsp. zooepidemicus. The causative organism did not possess any known GAS superantigen exotoxin genes but did show evidence of superantigen production.
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Group C streptococci have been reported to cause invasive disease similar to that classically associated with group A streptococcus (GAS). We describe a fatal case of toxic shock-like syndrome due to Streptococcus equi subsp. zooepidemicus. The causative organism did not possess any known GAS superantigen exotoxin genes but did show evidence of superantigen production.
Key concepts: Superantigen, Exotoxin, Toxic shock syndrome, Microbiology, Streptococcus pyogenes, Streptococcus, Group A, Biology