2008Synthetic CommunicationsRequires access

Synthesis of Ethyl Nicotinate-5-Boronic Acid Pinacol Ester and Its Application Toward Suzuki Coupling

Yves Leblanc, Pascal Cérat

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Abstract

A method for the synthesis and isolation of pure ethyl nicotinate-5-boronic acid pinacol ester has been described. This boronate ester was used to prepare C2-C5 heteroarylnicotinates in good yields.

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What this paper is about

A method for the synthesis and isolation of pure ethyl nicotinate-5-boronic acid pinacol ester has been described. This boronate ester was used to prepare C2-C5 heteroarylnicotinates in good yields.

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Available abstract

A method for the synthesis and isolation of pure ethyl nicotinate-5-boronic acid pinacol ester has been described. This boronate ester was used to prepare C2-C5 heteroarylnicotinates in good yields.

Key concepts: Pinacol, Chemistry, Boronic acid, Suzuki reaction, Coupling (piping), Organic chemistry, Ethyl ester, Phenylboronic acid

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