1966•PubMedRequires access
The cardiovascular pharmacology of lidoflazine, a long-acting coronary vasodilator.
Schaper Wk, R Xhoneux, Jageneau Ah, Patricia A. Janssen
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Abstract
A series of cardiovascular experiments with lidoflazine (R 7904) in anesthetized and unanesthetized dogs is described in detail. The results indicate that lidoflazine is a specific, orally active and very long-acting coronary vasodilating agent. It acts directly on the smooth muscles of the coronary vessels. Lidoflazine is chemically unrelated to the known coronary vasodilators.