1996•Clinical and Diagnostic Laboratory ImmunologyOpen access

A new procedure for the purification of streptococcal pyrogenic exotoxin A from Streptococcus pyogenes supernatant

Ellen M. Mascini, M A Hazenberg, Liesbeth Verhage, S. E. Holm, J. Verhoef, Johannes van Dijk

Abstract

An important role in the pathogenesis of invasive group A streptococcal disease has been ascribed to the production of streptococcal pyrogenic exotoxin A. We present a new technique for the purification of streptococcal pyrogenic exotoxin A from Streptococcus pyogenes NY-5 supernate, which is highly efficient with respect to yield (35%), purity (> or = 99%), and time.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 6 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Streptococcus pyogenes, Exotoxin, Microbiology, Streptococcus, STREPTOCOCCAL INFECTIONS, Chemistry, Group A, Streptococcaceae