1985Comprehensive physiologyRequires access

Blood Coagulation and Fibrinolysis

Robert W. Colman, Andrei Z. Budzynski

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Abstract

Abstract The sections in this article are: Congenital Deficiencies in Initiation of Blood Coagulation FactorXII Plasma Prekallikrein Plasma Kininogens Interaction of Contact‐System Proteins FactorXI FactorIX FactorVIII Relationship of Intrinsic and Extrinsic Blood Coagulation Factor X FactorVII Thromboplastin Regulation of Prothrombin Activation Prothrombin Factor V Coagulant Phospholipid Surfaces Calcium Ions Thrombin Formation Thrombin Specificity Regulation of Thrombin Activity Heparin and AntithrombinIII Interaction of Thrombin With Fibrin Nonmammalian Inhibitors of Thrombin Thrombinlike Enzymes in Snake Venoms Electron Microscopy of Fibrinogen Fibrinogen Structure Model of Fibrinogen Molecule Conversion of Fibrinogen to Fibrin Clot Polymerization Sites Cross‐Linking of Fibrin Interaction of Fibrinogen with Plasma Proteins Interaction of Fibrinogen with Cells Degradation by Proteases other than Plasmin Degradation of Fibrinogen and Fibrin by Plasmin Role of Fibrin in Clot Formation and Lysis Plasminogen and Plasmin Plasminogen Activators Inhibitors of Plasminogen and Plasmin Physiological Fibrinolysis

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What this paper is about

Abstract The sections in this article are: Congenital Deficiencies in Initiation of Blood Coagulation FactorXII Plasma Prekallikrein Plasma Kininogens Interaction of Contact‐System Proteins FactorXI FactorIX FactorVIII Relationship of Intrinsic and Extrinsic Blood Coagulation Factor X FactorVII Thromboplastin Regulation of Prothrombin Activation Prothrombin Factor V Coagulant Phospholipid Surfaces Calcium Ions Thrombin Formation Thrombin Specificity Regulation of Thrombin Activity Heparin and AntithrombinIII Interaction of Thrombin With Fibrin Nonmammalian Inhibitors of Thrombin Thrombinlike Enzymes in Snake Venoms Electron Microscopy of Fibrinogen Fibrinogen Structure Model of Fibrinogen Molecule Conversion of Fibrinogen to Fibrin Clot Polymerization Sites Cross‐Linking of Fibrin Interaction of Fibrinogen with Plasma Proteins Interaction of Fibrinogen with Cells Degradation by Proteases other than Plasmin Degradation of Fibrinogen and Fibrin by Plasmin Role of Fibrin in Clot Formation and Lysis Plasminogen and Plasmin Plasminogen Activators Inhibitors of Plasminogen and Plasmin Physiological Fibrinolysis

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Available abstract

Abstract The sections in this article are: Congenital Deficiencies in Initiation of Blood Coagulation FactorXII Plasma Prekallikrein Plasma Kininogens Interaction of Contact‐System Proteins FactorXI FactorIX FactorVIII Relationship of Intrinsic and Extrinsic Blood Coagulation Factor X FactorVII Thromboplastin Regulation of Prothrombin Activation Prothrombin Factor V Coagulant Phospholipid Surfaces Calcium Ions Thrombin Formation Thrombin Specificity Regulation of Thrombin Activity Heparin and AntithrombinIII Interaction of Thrombin With Fibrin Nonmammalian Inhibitors of Thrombin Thrombinlike Enzymes in Snake Venoms Electron Microscopy of Fibrinogen Fibrinogen Structure Model of Fibrinogen Molecule Conversion of Fibrinogen to Fibrin Clot Polymerization Sites Cross‐Linking of Fibrin Interaction of Fibrinogen with Plasma Proteins Interaction of Fibrinogen with Cells Degradation by Proteases other than Plasmin Degradation of Fibrinogen and Fibrin by Plasmin Role of Fibrin in Clot Formation and Lysis Plasminogen and Plasmin Plasminogen Activators Inhibitors of Plasminogen and Plasmin Physiological Fibrinolysis

Key concepts: Plasmin, Fibrinogen, Fibrin, Chemistry, Thrombin, Coagulation, Fibrinolysis, Prothrombinase

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