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2000•Organic LettersRequires access

Efficient One-Step Conversion of Primary Aliphatic Amines into Primary Alcohols: Application to a Model Study for the Total Synthesis of (±)-Scopadulin

S. M. Abdur Rahman, Hiroaki Ohno, Naoyoshi Maezaki, C. IWATA, Tetsuaki Tanaka

Open publisher page 29 citations

Abstract

[reaction: see text] Treatment of primary aliphatic amines with KOH in diethylene glycol at 210 degrees C gives primary alcohols directly in good yields. A synthetic application to a model study of (+/-)-scopadulin is also described.

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What this paper is about

[reaction: see text] Treatment of primary aliphatic amines with KOH in diethylene glycol at 210 degrees C gives primary alcohols directly in good yields. A synthetic application to a model study of (+/-)-scopadulin is also described.

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OpenAlex reports 29 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

[reaction: see text] Treatment of primary aliphatic amines with KOH in diethylene glycol at 210 degrees C gives primary alcohols directly in good yields. A synthetic application to a model study of (+/-)-scopadulin is also described.

Key concepts: Primary (astronomy), Chemistry, Diethylene glycol, Organic chemistry, Primary alcohol, Combinatorial chemistry, Catalysis, Ethylene glycol

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Efficient One-Step Conversion of Primary Aliphatic Amines into Primary Alcohols: Application to a Model Study for the Total Synthesis of (±)-Scopadulin — Research Paper | ScholarLens