Lactate Dehydrogenase Isoenzymes
Arthur F. Krieg, Lawrence Rosenblum, John B. Henry
Abstract
Arthur F. Krieg, Lawrence Rosenblum, John B. Henry
Abstract
Abstract Five lactate dehydrogenase isoenzymes are normally observed in human serum: H4 (LDH1), H3M (LDH2), H2M2 (LDH3), HM3 (LDH4), and M4 (LDH5). This study presents evidence that these isoenzymes vary in the ratio of LDH activity (pyruvate → lactate) to LDH activity (lactate → pyruvate).
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Abstract Five lactate dehydrogenase isoenzymes are normally observed in human serum: H4 (LDH1), H3M (LDH2), H2M2 (LDH3), HM3 (LDH4), and M4 (LDH5). This study presents evidence that these isoenzymes vary in the ratio of LDH activity (pyruvate → lactate) to LDH activity (lactate → pyruvate).
Key concepts: Lactate dehydrogenase, Isozyme, L-Lactate dehydrogenase, Dehydrogenase, Chemistry, Biochemistry, Enzyme