알코올 의존 환자들의 충동성, 감각추구, 인지기능 및 상호 관련성

Objectives：The aim of this study was to investigate impulsivity, sensation seeking, and cognitive function, and to examine whether impulsivity or sensation seeking would be related with possible cognitive impairments in patients with alcohol dependence. \n Methods：Thirty hospitalized patients with alcohol dependence and 30 healthy volunteers were enrolled in this study. All participants were male and completed the Barratt Impulsiveness Scale, the Zuckerman Sensation Seeking Scale, the Wisconsin Card Sorting Test(WCST), the trail making test(TMT), and the Stroop task. \n Results：The performance on the Wisconsin Card Sorting Test, the Trail Making Test, and the Stroop task of alcoholic group were significantly poorer than that of control group. Patients with alcohol dependence scored higher than controls in total and motor impulsiveness subscale scores of the Barratt Impulsiveness Scale (p＜0.05, p＜0.01, respectively). But, no significant group difference was found in the Zuckerman Sensation Seeking Scale. Within alcoholic group, scores of the Barratt Impulsiveness Scale or the Zuckerman Sensation Seeking Scale were not correlated with any neurocognitive tests. \n Conclusion：Patients with alcohol dependence may be more impulsive and impair cognitive function than normal control. However, we failed to find the relationships between cognitive function and impulsivity or sensation seeking in patients with alcohol dependence.