1985Recueil des Travaux Chimiques des Pays-BasRequires access

On the bromination of 1,2,3‐triphenylazulene

Peter de Wit, Hans J. A. Lambrechts, Hans Cerfontain

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Abstract

Abstract The bromination of 1,2,3‐triphenylazulene (1) with a tenfold excess of bromine in CHCl3/CCl4 as solvent yields 5,7‐dibromo‐1,3‐bis(p‐bromophenyl)‐2‐phenylazulene and not a dibromo derivative as reported earlier1,2. With 1.0 equivalent of bromine or 2.0 equivalents of NBS, a mixture of the 5‐bromo and 5,7‐dibromo derivatives of 1 is obtained.

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Abstract The bromination of 1,2,3‐triphenylazulene (1) with a tenfold excess of bromine in CHCl3/CCl4 as solvent yields 5,7‐dibromo‐1,3‐bis(p‐bromophenyl)‐2‐phenylazulene and not a dibromo derivative as reported earlier1,2. With 1.0 equivalent of bromine or 2.0 equivalents of NBS, a mixture of the 5‐bromo and 5,7‐dibromo derivatives of 1 is obtained.

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Available abstract

Abstract The bromination of 1,2,3‐triphenylazulene (1) with a tenfold excess of bromine in CHCl3/CCl4 as solvent yields 5,7‐dibromo‐1,3‐bis(p‐bromophenyl)‐2‐phenylazulene and not a dibromo derivative as reported earlier1,2. With 1.0 equivalent of bromine or 2.0 equivalents of NBS, a mixture of the 5‐bromo and 5,7‐dibromo derivatives of 1 is obtained.

Key concepts: Halogenation, Bromine, Derivative (finance), Chemistry, Solvent, Medicinal chemistry, Organic chemistry, Economics

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