1999•Biochemical and Biophysical Research CommunicationsRequires access

Nitrogen-Containing Bisphosphonates Inhibit Isopentenyl Pyrophosphate Isomerase/Farnesyl Pyrophosphate Synthase Activity with Relative Potencies Corresponding to Their Antiresorptive Potenciesin Vitroandin Vivo

Ermond van Beek, Elsbet Pieterman, Louis Cohen, Clemens W.G.M. Löwik, Socrates E. Papapoulos

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Key concepts: Farnesyl pyrophosphate, Isopentenyl pyrophosphate, Geranylgeranyl pyrophosphate, Pyrophosphate, Chemistry, Farnesyl diphosphate synthase, Biochemistry, In vivo