2012•Journal of Solid TumorsOpen access

Tumor markers and kinetics in prostate cancer: a mini-review

Farooq Ahmad Ganie, Mohd Lateef Wani, Shadab Nabi Wani, Mohd Saleem Wani, Ab Gani Ahangar, Shabir Ahmad Ganie, Nasir-U-Din Wani, Mubasher Ahmad Bhat

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Abstract

The discovery and utilization of tumor markers have affected early detection, diagnosis, and staging and follow up of Prostate cancer and have improved curative rates. The goal of identifying different tumor markers in prostate cancer is to get the early diagnosis. One can also see the effect of treatment modality used and prognosticate the disease. In this review we intend to give a detailed account of different markers in prostate cancer. Besides Prostate Specific Antigen, Human kallikrein 2, Kallikrein-related peptidase 14, Prostate acid phosphatase, Cancer Antigen 15-3, Prostate-specific membrane antigen etc. are discussed in detail.

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The discovery and utilization of tumor markers have affected early detection, diagnosis, and staging and follow up of Prostate cancer and have improved curative rates. The goal of identifying different tumor markers in prostate cancer is to get the early diagnosis. One can also see the effect of treatment modality used and prognosticate the disease. In this review we intend to give a detailed account of different markers in prostate cancer. Besides Prostate Specific Antigen, Human kallikrein 2, Kallikrein-related peptidase 14, Prostate acid phosphatase, Cancer Antigen 15-3, Prostate-specific membrane antigen etc. are discussed in detail.

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Available abstract

The discovery and utilization of tumor markers have affected early detection, diagnosis, and staging and follow up of Prostate cancer and have improved curative rates. The goal of identifying different tumor markers in prostate cancer is to get the early diagnosis. One can also see the effect of treatment modality used and prognosticate the disease. In this review we intend to give a detailed account of different markers in prostate cancer. Besides Prostate Specific Antigen, Human kallikrein 2, Kallikrein-related peptidase 14, Prostate acid phosphatase, Cancer Antigen 15-3, Prostate-specific membrane antigen etc. are discussed in detail.

Key concepts: Prostate cancer, Kallikrein, Medicine, Prostate-specific antigen, Oncology, Glutamate carboxypeptidase II, PCA3, Cancer

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