2010•Pharmaceutical Sciences EncyclopediaRequires access

Production and Purification of Adenovirus Vectors for Gene Therapy

D.M.F. Prazeres, José A. L. Santos

Abstract

Abstract Gene therapy is a simple and attractive process which consists of the introduction of one or more functional genes in a human or non‐human receptor. Most recombinant viral vectors used in gene therapy clinical trials belong to adenovirus, retrovirus/lentivirus, pox/vaccinia virus, and adeno‐associated virus. This article focuses on adenovirus vector for gene therapy.

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Available abstract

Key concepts: Genetic enhancement, Retrovirus, Virology, Vectors in gene therapy, Viral vector, Vector (molecular biology), Recombinant virus, Gene