Chemical studies of marine invertebrates. XXXVII(1). Three novel meroditerpenoids from the sponge strongylophora durissima(2).

Abstract Three novel meroditerpenoids, strongylophorine‐1 (1), ‐2 (2) and ‐3 (3) have been isolated from the sponge Strongylophora durissima, Strongylophorine‐1 and ‐3 possess structure 1 and 3 respectively, as established by their spectral properties, hemisynthesis and chemical intercorrelation. The structure of strongylophorine‐2 has been shown to be 2 by X‐ray diffraction analysis on its monoacetylderivative (13).