1993•Journal of Clinical MicrobiologyOpen access

Prevalence of antibodies to spotted fever group rickettsiae along the eastern coast of the Adriatic sea

Suzana Radulović, David Hughes Walker, Kimberly Weiss, Boris Dželalija, Miro Morović

Abstract

A seroepidemiological survey in coastal Croatia detected antibodies reactive with Rickettsia conorii in 4.2% of sera by immunofluorescence assay and in 5.0% of sera by enzyme immunoassay. Western immunoblotting demonstrated antibodies to the 120-kDa surface protein in all 20 positive serum samples examined and to rickettsial lipopolysaccharide in 3 of these serum samples. Humans in this area are clearly being exposed to spotted fever rickettsiae.

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Key concepts: Spotted fever, Boutonneuse fever, Rickettsia conorii, Rickettsiosis, Rickettsia, Antibody, Rickettsiaceae, Immunoassay