Platelet Aggregation Tests Are Affected in Pseudothrombocytopenia: Table 1

Objective: The aim of the study is to evaluate the platelet functions with platelet aggregation tests in patients with pseudothrombocytopenia (PTCP). Methods: Fifteen (9 female and 6 male) patients with a mean age of 48 ± 4 years with PTCP (platelet count below 150 × 10 3 /µL) and 19 (13 female and 6 male) healthy controls with a mean age of 55 ± 2 years were enrolled in this study. In both groups, whole blood counts, peripheral smear, and platelet aggregation tests including ristocetin, epinephrine, collagen, and ADP were investigated. Results: Adenosine diphosphate (ADP) 63 ± 6% and epinephrine-induced 61 ± 5% platelet aggregations in the patients with PTCP were significantly lower in those of healthy controls 93 ± 3.5% and 80 ± 4%, respectively, and P=0.001 and P=0.006, respectively. Conclusion: Platelet aggregation tests may decrease in PTCP, but its importance is unclear. Therefore, this condition should be investigated with larger series and molecular studies.