2002•European Journal of Organic ChemistryRequires access

Synthesis of 5-Substituted 2,2′-Bipyridines from Substituted 2-Chloropyridines by a Modified Negishi Cross-Coupling Reaction

Arne Lützen, Marko Hapke

Abstract

A new and practical approach to a number of differently 5-substituted 2,2′-bipyridines starting from substituted 2-chloropyridines has been found through the application of modified Negishi cross-coupling conditions. (© Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)

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Key concepts: Negishi coupling, Chemistry, Coupling (piping), Coupling reaction, Computational chemistry, Combinatorial chemistry, Organic chemistry, Catalysis