2010•Journal of the Association of Nurses in AIDS CareRequires access

Screening and Management of Anal Dysplasia and Anal Cancer in HIV-Infected Patients: A Guide for Practice

Matt Moran, Thomas W. Barkley, Cynthia Bach Hughes

Abstract

People living with HIV infection have a significantly higher rate of anal cancer as compared with that of uninfected people. It is believed that high-grade anal dysplasia secondary to human papillomavirus infection is a precursor to anal cancer. Considering this, screening and treatment of high-grade anal dysplasia is a possible means of preventing the development of anal cancer. No national or international guidelines exist to guide practice for screening and management of anal dysplasia. On the basis of a review of research and expert recommendations, a guide to practice for screening and management of anal dysplasia and anal cancer is made for clinicians.

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Key concepts: Anal cancer, Dysplasia, Medicine, Human immunodeficiency virus (HIV), Gynecology, Dermatology, Family medicine, Internal medicine