ScholarLens Back to search
1986•Angewandte Chemie International Edition in EnglishRequires access

Reactivity of Anionic Pentacoordinated Silicon Complexes towards Nucleophiles

Alain Boudin, Geneviève Cerveau, Claude Chuit, Robert J. P. Corriu, Catherine Reyé

Open publisher page 48 citations

Abstract

Steric hindrance seldom plays a role in nucleophilic substitutions at silicon, since the pentacoordinated Si anions of 1, R, R = Me, Ph, 1-naphthyl, react far more rapidly with nucleophiles, e.g. PhMgBr, than the neutral compound 2. “By-products” of the reactivity study are new synthetic methods for RSiH3, RR′2SiH, and RSiR′3 (R′ = alkyl, aryl).

About this research paper

What this paper is about

Steric hindrance seldom plays a role in nucleophilic substitutions at silicon, since the pentacoordinated Si anions of 1, R, R = Me, Ph, 1-naphthyl, react far more rapidly with nucleophiles, e.g. PhMgBr, than the neutral compound 2. “By-products” of the reactivity study are new synthetic methods for RSiH3, RR′2SiH, and RSiR′3 (R′ = alkyl, aryl).

Why it matters

OpenAlex reports 48 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Steric hindrance seldom plays a role in nucleophilic substitutions at silicon, since the pentacoordinated Si anions of 1, R, R = Me, Ph, 1-naphthyl, react far more rapidly with nucleophiles, e.g. PhMgBr, than the neutral compound 2. “By-products” of the reactivity study are new synthetic methods for RSiH3, RR′2SiH, and RSiR′3 (R′ = alkyl, aryl).

Key concepts: Nucleophile, Steric effects, Reactivity (psychology), Chemistry, Alkyl, Aryl, Silicon, Medicinal chemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Reactivity of Anionic Pentacoordinated Silicon Complexes towards Nucleophiles — Research Paper | ScholarLens