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2008•Clinical Infectious DiseasesOpen access

Early Sequential Development of Infective Dermatitis, Human T Cell Lymphotropic Virus Type 1-Associated Myelopathy, and Adult T Cell Leukemia/Lymphoma

Lourdes Farré, Maria de Fátima Paim de Oliveira, Janeusa Primo, Anne‐Mieke Vandamme, Johan Van Weyenbergh, Achiléa Lisbôa Bittencourt

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Abstract

We describe a patient with human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis who developed HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia/lymphoma at 16 years of age. Long inverse polymerase chain reaction was used to demonstrate monoclonal integration of proviral DNA in the lymphomatous skin lesion.

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We describe a patient with human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis who developed HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia/lymphoma at 16 years of age. Long inverse polymerase chain reaction was used to demonstrate monoclonal integration of proviral DNA in the lymphomatous skin lesion.

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Available abstract

We describe a patient with human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis who developed HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia/lymphoma at 16 years of age. Long inverse polymerase chain reaction was used to demonstrate monoclonal integration of proviral DNA in the lymphomatous skin lesion.

Key concepts: Tropical spastic paraparesis, Medicine, Myelopathy, Lymphoma, Leukemia, Human T-lymphotropic virus 1, Virology, Adult T-cell leukemia/lymphoma

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Early Sequential Development of Infective Dermatitis, Human T Cell Lymphotropic Virus Type 1-Associated Myelopathy, and Adult T Cell Leukemia/Lymphoma — Research Paper | ScholarLens