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1999•Journal of BacteriologyOpen access

A New Class of Cobalamin Transport Mutants ( btuF ) Provides Genetic Evidence for a Periplasmic Binding Protein in Salmonella typhimurium

Michael Van Bibber, Clive Bradbeer, Nica Clark, John R. Roth

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Abstract

No periplasmic binding protein has been demonstrated for the ATP-binding cassette (ABC)-type cobalamin transporter BtuCD. New mutations (btuF) are described that affect inner-membrane transport. The BtuF protein has a signal sequence and resembles the periplasmic binding proteins of several other ABC transporters.

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What this paper is about

No periplasmic binding protein has been demonstrated for the ATP-binding cassette (ABC)-type cobalamin transporter BtuCD. New mutations (btuF) are described that affect inner-membrane transport. The BtuF protein has a signal sequence and resembles the periplasmic binding proteins of several other ABC transporters.

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OpenAlex reports 31 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

No periplasmic binding protein has been demonstrated for the ATP-binding cassette (ABC)-type cobalamin transporter BtuCD. New mutations (btuF) are described that affect inner-membrane transport. The BtuF protein has a signal sequence and resembles the periplasmic binding proteins of several other ABC transporters.

Key concepts: Periplasmic space, Biology, ATP-binding cassette transporter, Membrane transport protein, Biochemistry, Transport protein, Bacterial outer membrane, Binding protein

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