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Successful treatment of 75 patients in status epilepticus with intravenous midazolam

G MICHAEL GALVIN, George Alexander Jelinek

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Abstract

ABSTRACT Seventy‐five consecutive patients attending the Emergency Department at Fremantle Hospital in status epilepticus were treated with intravenous midazolam. All seizures ceased without other therapy, after an average dose of 0.1 mg/kg midazolam. Seven percent of patients had a further seizure in the Emergency Department, a rate comparable to other anticonvulsants. Midazolam is a safe, effective agent for the treatment of status epilepticus, with possible advantages over currently accepted treatment.

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What this paper is about

ABSTRACT Seventy‐five consecutive patients attending the Emergency Department at Fremantle Hospital in status epilepticus were treated with intravenous midazolam. All seizures ceased without other therapy, after an average dose of 0.1 mg/kg midazolam. Seven percent of patients had a further seizure in the Emergency Department, a rate comparable to other anticonvulsants. Midazolam is a safe, effective agent for the treatment of status epilepticus, with possible advantages over currently accepted treatment.

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OpenAlex reports 8 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

ABSTRACT Seventy‐five consecutive patients attending the Emergency Department at Fremantle Hospital in status epilepticus were treated with intravenous midazolam. All seizures ceased without other therapy, after an average dose of 0.1 mg/kg midazolam. Seven percent of patients had a further seizure in the Emergency Department, a rate comparable to other anticonvulsants. Midazolam is a safe, effective agent for the treatment of status epilepticus, with possible advantages over currently accepted treatment.

Key concepts: Midazolam, Status epilepticus, Medicine, Emergency department, Anesthesia, Epilepsy, Psychiatry, Sedation

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