2012•Bioorganic & Medicinal Chemistry LettersOpen access

Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV

John I. Manchester, Daemian D. Dussault, Jonathan A. Rose, P. Ann Boriack‐Sjodin, Maria Uria-Nickelsen, Georgine Ioannidis, Shanta Bist, Paul Fleming, Kenneth G. Hull

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Key concepts: DNA gyrase, Topoisomerase, Topoisomerase IV, Chemistry, DNA, Topoisomerase inhibitor, Antibacterial agent, Antibiotics

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