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ChemInform Abstract: One‐Pot Synthesis of 4‐Substituted 3,4‐Dihydro‐3‐methoxyisocoumarins via Carboxylation of α‐Substituted 2‐Lithio‐β‐methoxystyrenes with Carbon Dioxide.

Kazuhiro Kobayashi, Toshiyuki Nagaoka, Yuu Shirai, Wataru Miyatani, Yuki Yokoi, Hisatoshi Konishi

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Abstract

Abstract Carboxylation of α‐substituted 2‐lithio‐β‐methoxystyrenes followed by acid‐mediated lactonization opens a convenient route to the title compounds.

About this research paper

What this paper is about

Abstract Carboxylation of α‐substituted 2‐lithio‐β‐methoxystyrenes followed by acid‐mediated lactonization opens a convenient route to the title compounds.

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Available abstract

Abstract Carboxylation of α‐substituted 2‐lithio‐β‐methoxystyrenes followed by acid‐mediated lactonization opens a convenient route to the title compounds.

Key concepts: Carboxylation, Chemistry, Carbon dioxide, Organic chemistry, Medicinal chemistry, Catalysis

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ChemInform Abstract: One‐Pot Synthesis of 4‐Substituted 3,4‐Dihydro‐3‐methoxyisocoumarins via Carboxylation of α‐Substituted 2‐Lithio‐β‐methoxystyrenes with Carbon Dioxide. — Research Paper | ScholarLens