2010Journal of Heterocyclic ChemistryRequires access

Synthesis of tetrahetrocyclic systems including pyrido[2′,3′:3,4]pyrazolo[1,5‐a]pyrimidine fused with pyrazole derivatives and isolated with 1,3,4‐oxa‐, thiadiazole, and 1,2,4‐tetrazole derivatives

Farag A. El‐Essawy

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Abstract

Abstract magnified image A series of isolated and fused tetracyclic compounds, containing pyrido[2′,3′:3,4]pyrazolo[1,5‐a]pyrimidine linked with 1,3,4‐oxa‐, thiadiazole, 1,2,4‐tetrazole, and pyrazole derivatives were prepared by the reaction of 1,8,10‐trimethyl‐4‐oxo‐1,4‐dihydropyrido[2′,3′:3,4]pyrazolo[1,5‐a]pyrimidine‐3‐carboxylate and some common reagents to provide the product in satisfactory yields. J. Heterocyclic Chem., (2010).

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Abstract magnified image A series of isolated and fused tetracyclic compounds, containing pyrido[2′,3′:3,4]pyrazolo[1,5‐a]pyrimidine linked with 1,3,4‐oxa‐, thiadiazole, 1,2,4‐tetrazole, and pyrazole derivatives were prepared by the reaction of 1,8,10‐trimethyl‐4‐oxo‐1,4‐dihydropyrido[2′,3′:3,4]pyrazolo[1,5‐a]pyrimidine‐3‐carboxylate and some common reagents to provide the product in satisfactory yields. J. Heterocyclic Chem., (2010).

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Available abstract

Abstract magnified image A series of isolated and fused tetracyclic compounds, containing pyrido[2′,3′:3,4]pyrazolo[1,5‐a]pyrimidine linked with 1,3,4‐oxa‐, thiadiazole, 1,2,4‐tetrazole, and pyrazole derivatives were prepared by the reaction of 1,8,10‐trimethyl‐4‐oxo‐1,4‐dihydropyrido[2′,3′:3,4]pyrazolo[1,5‐a]pyrimidine‐3‐carboxylate and some common reagents to provide the product in satisfactory yields. J. Heterocyclic Chem., (2010).

Key concepts: Chemistry, Pyrimidine, Pyrazole, Tetrazole, Reagent, Stereochemistry, Medicinal chemistry, Carboxylate

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Synthesis of tetrahetrocyclic systems including pyrido[2′,3′:3,4]pyrazolo[1,5‐a]pyrimidine fused with pyrazole derivatives and isolated with 1,3,4‐oxa‐, thiadiazole, and 1,2,4‐tetrazole derivatives — Research Paper | ScholarLens