Inverse Effects of Purified Hypothalamic TRF on the Acute Secretion of TSH and ACTH
E Sakiz, Roger Guillemin
Abstract
E Sakiz, Roger Guillemin
Abstract
When the pituitary is induced to secrete TSH by TRF it concomitantly secretes less ACTH in response to stress; conversely, when the secretion of ACTH is inhibited as by pretreatment with dexamethasone and Nembutal, the pituitary secretes higher quantities of TSH in response to TRF. (Endocrinology77: 797, 1965)
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When the pituitary is induced to secrete TSH by TRF it concomitantly secretes less ACTH in response to stress; conversely, when the secretion of ACTH is inhibited as by pretreatment with dexamethasone and Nembutal, the pituitary secretes higher quantities of TSH in response to TRF. (Endocrinology77: 797, 1965)
Key concepts: Endocrinology, Internal medicine, Secretion, ACTH secretion, Dexamethasone, Pituitary gland, Adrenocorticotropic hormone, Medicine