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2015•Brazilian Journal of NephrologyOpen access

Contrast-induced nephropathy after computed tomography

Luciano da Silva Selistre, V. de Souza, Laurence Dubourg, Mário Bernardes Wagner, João Rubião Höefel Filho, David Saitovitch

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Abstract

INTRODUCTION: Contrast induced nephropathy is the third most prevalent preventable cause of acute kidney injury in hospitalized patients. It defined as an absolute increase in serum creatinine ≥ 0.5 mg/dL and relative ≥ 25% increase. OBJECTIVE: We studied the risk factors to intravenous injection contrast nephropathy after computed tomography. METHODS: We studied 400 patients prospectively. RESULTS: The incidence of contrast induced nephropathy, with an absolute or a relative increase were 4.0% and 13.9%, respectively. Diabetes and cardiac failure were independent risk factors for CIN a relative increase de serum creatinine (O.R.: 3.5 [95% CI: 1.92-6.36], p < 0.01, 2.61 [95% CI: 1.14-6.03%], p < 0.05, respectively). CONCLUSIONS: We showed association between uses of intravenous injection contrast after computed tomography with acute injury renal, notably with diabetes and heart failure.

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INTRODUCTION: Contrast induced nephropathy is the third most prevalent preventable cause of acute kidney injury in hospitalized patients. It defined as an absolute increase in serum creatinine ≥ 0.5 mg/dL and relative ≥ 25% increase. OBJECTIVE: We studied the risk factors to intravenous injection contrast nephropathy after computed tomography. METHODS: We studied 400 patients prospectively. RESULTS: The incidence of contrast induced nephropathy, with an absolute or a relative increase were 4.0% and 13.9%, respectively. Diabetes and cardiac failure were independent risk factors for CIN a relative increase de serum creatinine (O.R.: 3.5 [95% CI: 1.92-6.36], p < 0.01, 2.61 [95% CI: 1.14-6.03%], p < 0.05, respectively). CONCLUSIONS: We showed association between uses of intravenous injection contrast after computed tomography with acute injury renal, notably with diabetes and heart failure.

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Available abstract

INTRODUCTION: Contrast induced nephropathy is the third most prevalent preventable cause of acute kidney injury in hospitalized patients. It defined as an absolute increase in serum creatinine ≥ 0.5 mg/dL and relative ≥ 25% increase. OBJECTIVE: We studied the risk factors to intravenous injection contrast nephropathy after computed tomography. METHODS: We studied 400 patients prospectively. RESULTS: The incidence of contrast induced nephropathy, with an absolute or a relative increase were 4.0% and 13.9%, respectively. Diabetes and cardiac failure were independent risk factors for CIN a relative increase de serum creatinine (O.R.: 3.5 [95% CI: 1.92-6.36], p < 0.01, 2.61 [95% CI: 1.14-6.03%], p < 0.05, respectively). CONCLUSIONS: We showed association between uses of intravenous injection contrast after computed tomography with acute injury renal, notably with diabetes and heart failure.

Key concepts: Contrast-induced nephropathy, Medicine, Nephropathy, Creatinine, Acute kidney injury, Diabetes mellitus, Relative risk, Diabetic nephropathy

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