2014Seminars in OphthalmologyRequires access

Positive Response to Methylprednisolone in a Child with Reactive Lymphoid Hyperplasia of the Conjunctiva

Agata Brązert, Anna Gotz‐Więckowska

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Abstract

The aim of this paper is to present the case of a child with reactive lymphoid hyperplasia of the conjunctiva, whose lesion regressed completely after oral glucocorticosteroid treatment. The final diagnosis was established on the basis of a histopathological examination combined with an immunohistochemical staining test and the exclusion of other conditions that could generate similar lesions. Because of the lack of general contraindications, methylprednisolone treatment was administered and local improvement was obtained. Reactive lymphoid hyperplasia of the conjunctiva is rarely found in children. It is important to emphasize the fact that lymphoproliferative lesions in the conjunctiva may, on the one hand, represent a lymphoma; on the other hand, they may be caused by a benign lesion-reactive lymphoid hyperplasia of the conjunctiva. Many treatment methods have been reported in the literature on the subject, but there are no clear guidelines concerning therapy in children.

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What this paper is about

The aim of this paper is to present the case of a child with reactive lymphoid hyperplasia of the conjunctiva, whose lesion regressed completely after oral glucocorticosteroid treatment. The final diagnosis was established on the basis of a histopathological examination combined with an immunohistochemical staining test and the exclusion of other conditions that could generate similar lesions. Because of the lack of general contraindications, methylprednisolone treatment was administered and local improvement was obtained. Reactive lymphoid hyperplasia of the conjunctiva is rarely found in children. It is important to emphasize the fact that lymphoproliferative lesions in the conjunctiva may, on the one hand, represent a lymphoma; on the other hand, they may be caused by a benign lesion-reactive lymphoid hyperplasia of the conjunctiva. Many treatment methods have been reported in the literature on the subject, but there are no clear guidelines concerning therapy in children.

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Available abstract

The aim of this paper is to present the case of a child with reactive lymphoid hyperplasia of the conjunctiva, whose lesion regressed completely after oral glucocorticosteroid treatment. The final diagnosis was established on the basis of a histopathological examination combined with an immunohistochemical staining test and the exclusion of other conditions that could generate similar lesions. Because of the lack of general contraindications, methylprednisolone treatment was administered and local improvement was obtained. Reactive lymphoid hyperplasia of the conjunctiva is rarely found in children. It is important to emphasize the fact that lymphoproliferative lesions in the conjunctiva may, on the one hand, represent a lymphoma; on the other hand, they may be caused by a benign lesion-reactive lymphoid hyperplasia of the conjunctiva. Many treatment methods have been reported in the literature on the subject, but there are no clear guidelines concerning therapy in children.

Key concepts: Medicine, Conjunctiva, Lymphoid hyperplasia, Pathology, Hyperplasia, Lesion, Pseudolymphoma, Methylprednisolone

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Positive Response to Methylprednisolone in a Child with Reactive Lymphoid Hyperplasia of the Conjunctiva — Research Paper | ScholarLens